Studied at the Rotter School of Advertising Graphics in Prague (1937–1938) and at the Academy of Arts, Architecture and Design in Prague (1945–1950; Emil Filla). Created over 289 posters in his life.

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<ref name=CH>{{cite web |url=https://collection.cooperhewitt.org/people/18063465/ |title=Karel Vaca |author=Cooper Hewitt, Smithsonian Design Museum |accessdate=15 January 2026 |publisher=Smithsonian Institution}}</ref>